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VETERINARY TEAM REFERENCE · MEDICATION

Pregabalin

A nervous-system medication with distinct veterinary and human products. Bonqat is a feline oral solution for transportation- and veterinary-visit-related anxiety and fear. Lyrica is a human formulation; veterinary use of that product requires separate species-specific prescribing.

Alpha2-delta calcium-channel ligandProduct-specific clinical reference

Updated October 16, 2026 · Sources and review status below

For veterinarians and veterinary staff. Product-label information is distinct from extra-label clinical practice. This is not a complete prescribing formulary or an automated interaction screen. Verify the current label, exact formulation, patient and species-specific clinical reference before use. Independent veterinary/pharmacy review remains pending.

Prescribing overview

Bonqat and human Lyrica require distinct prescribing instructions.

Key prescribing checks

  • Renal elimination is clinically important; the prescriber should review kidney function before selecting the regimen.
  • Sedation, dizziness and impaired coordination are recognized label safety issues. Review concurrent opioids and other sedating medicines and investigate excessive sedation or respiratory difficulty.
  • The human label calls for gradual withdrawal. Do not abruptly stop a veterinarian-directed anticonvulsant plan or import the human taper schedule as an animal protocol.

Uses by species

Approval and evidence apply to the named product, species, route and indication. An extra-label use requires its own prescribing assessment; a human indication is not an animal approval.

Cats

FDA-approved

Acute anxiety/fear associated with transportation and veterinary visits

Safety below 7 months, breeding/pregnancy/lactation unestablished.

Use / indication source ↗

Pharmacology & pharmacokinetics

Mechanism and clinical role

Reduces neuronal calcium influx/neurotransmitter release.

Absorption, distribution, metabolism and elimination

Cats: oral bioavailability 94.3%; peak 0.5–1 hour; oral elimination half-life about 14.7 hours.

SAFETY REFERENCE · PRODUCT & SPECIES SPECIFIC

Contraindications & cautions

Contraindications identify circumstances where the source says a product should not be used. Precautions call for assessment or monitoring. Interactions identify combinations to review. They are distinct categories; this summary does not replace a full interaction check or the current product label.

Lyrica

Human immediate-release pregabalin capsules; veterinary use is extra-label.

Contraindications · when not to use

  • Pregabalin or ingredient hypersensitivity.

Precautions & monitoring

  • Angioedema, sedation and respiratory depression can occur. Review renal function and avoid abrupt withdrawal.

Bonqat

Feline 50 mg/mL oral solution only; not Lyrica capsules.

Contraindications · when not to use

  • Pregabalin or excipient hypersensitivity.

Precautions & monitoring

  • Caution: cardiac disease, hypertension, renal disease or severe systemic disorders. Safety below 7 months and in breeding/pregnant/lactating cats is unestablished.

Safety sources checked: . Selected label information; independent veterinary or veterinary-pharmacy review remains pending. A label for dogs, cats, horses or humans does not establish safety for another species.

Adverse effects

Ataxia, lethargy, vomiting, hypothermia and tremor may occur.

These are selected source-reported effects, not incidence estimates or an exhaustive list. Spontaneous postmarketing reports do not by themselves establish frequency or causality.

Dosing & administration

Verify the source before prescribing. The regimens below summarize selected veterinary product labels, not every accepted veterinary use. They are not automatic substitutions between brands or formulations. Renal/hepatic disease, concurrent therapy, age, indication and clinical response can require a different plan.
Selected product-label regimens — not a patient-specific prescription
Species & indicationLabeled regimenEligibility & source
CatsTransportation/veterinary-visit anxiety and fearBonqat 50 mg/mL oral solution

5 mg/kg (0.1 mL/kg)

Oral · Single dose approximately 1.5 hours before event

May be given on two consecutive days

Small amount of food permitted; no independent redosing.

Verify full dosing label ↗

No veterinary Lyrica capsule regimen verified.

Extra-label prescribing and food-animal residue requirements are separate from labeled regimens. FDA extra-label-use guidance ↗

Drug & supplement interactions

This is a selected interaction reference, not an automated or comprehensive combination checker. Reconcile prescription drugs, nonprescription products, supplements and recent treatment changes.

Lyrica

Human immediate-release pregabalin capsules; veterinary use is extra-label.

  • Opioids and other CNS depressants increase sedation/respiratory risk; ACE inhibitors can increase angioedema concern.
Interaction source ↗

Bonqat

Feline 50 mg/mL oral solution only; not Lyrica capsules.

  • Safety with opioids or other sedatives is unestablished.
Interaction source ↗

Monitoring

Assess comorbidities/sedatives; observe recovery.

Client counseling

Do not redose after spitting, vomiting, salivation or apparent nonresponse. Keep overly sedated cats warm; withhold food/water until effects resolve.

This section supports the veterinary team's discharge discussion; it does not replace the product’s Client Information Sheet where one is required.

Storage & handling

Bonqat: 2–8°C; use within 6 months opening; up to 1 month may be at ≤25°C.

Brands, formulations & ingredient identity

Active ingredients

Pregabalin

Lyrica contains pregabalin, not gabapentin. Related drug classes do not make these two active ingredients synonymous.

Confirm whether a prescription refers to capsules, solution or a modified-release product. An immediate-release product and a controlled-release product should not be substituted from a name match alone.

Human labeling does not transfer indications or administration instructions to an animal. Record the exact strength and dispensing instructions in medication reconciliation.

Shared ingredients do not establish interchangeable concentrations, routes, release properties, species labeling or regional availability.

Lyrica

Formulation
Oral capsules
Label / product scope
Human product

Human-labeled pregabalin; this lookup does not imply animal approval.

Product label / source ↗

Bonqat

Formulation
Pregabalin 50 mg/mL oral solution
Label / product scope
Cats

FDA-approved feline transportation/veterinary-visit anxiety treatment; Schedule V.

Product label / source ↗

References & review status

Clinical reference updated October 16, 2026. Independent veterinary or veterinary-pharmacy review not yet completed. Evidence gaps remain explicitly identified; this page does not claim equivalence to a comprehensive, professionally reviewed veterinary formulary.

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