Prescribing overview
Sterile antibiotic eye solution; it contains no corticosteroid.
Key prescribing checks
- Avoid use with known hypersensitivity to any component; neomycin sensitization is a labeled concern.
- Prolonged antibiotic use can permit nonsusceptible organisms to grow. Reassess persistence or worsening rather than substituting another abbreviated eye product without an examination.
Uses by species
Approval and evidence apply to the named product, species, route and indication. An extra-label use requires its own prescribing assessment; a human indication is not an animal approval.
Dogs and cats
Extra-labelSusceptible superficial bacterial ocular infection
Human-labeled product; veterinary diagnosis and prescription required.
Use / indication source ↗Pharmacology & pharmacokinetics
Mechanism and clinical role
Neomycin disrupts bacterial protein synthesis; polymyxin B and gramicidin alter bacterial membranes.
Absorption, distribution, metabolism and elimination
Animal-specific pharmacokinetic parameters were not established by the reviewed label.
SAFETY REFERENCE · PRODUCT & SPECIES SPECIFIC
Contraindications & cautions
Contraindications identify circumstances where the source says a product should not be used. Precautions call for assessment or monitoring. Interactions identify combinations to review. They are distinct categories; this summary does not replace a full interaction check or the current product label.
Neomycin + polymyxin B + gramicidin (ophthalmic)
Human-labeled Bausch + Lomb ophthalmic solution; veterinary use is extra-label.
Contraindications · when not to use
- Known allergy to any ingredient.
Precautions & monitoring
- Neomycin sensitization, resistant-organism overgrowth and bottle contamination can complicate treatment; never inject into the eye.
Safety sources checked: . Selected label information; independent veterinary or veterinary-pharmacy review remains pending. A label for dogs, cats, horses or humans does not establish safety for another species.
Adverse effects
Sensitization, local irritation and resistant-organism overgrowth are label concerns.
These are selected source-reported effects, not incidence estimates or an exhaustive list. Spontaneous postmarketing reports do not by themselves establish frequency or causality.
Dosing & administration
A verified veterinary dose has not been entered for this product. Human-label dosing must not be used as an animal regimen. Consult a current species-specific clinical source and the prescribing veterinarian.
A veterinary dose was not verified; human eye-drop schedules are not animal dosing instructions.
Extra-label prescribing and food-animal residue requirements are separate from labeled regimens. FDA extra-label-use guidance ↗
Drug & supplement interactions
This is a selected interaction reference, not an automated or comprehensive combination checker. Reconcile prescription drugs, nonprescription products, supplements and recent treatment changes.
Identified formulation
Human-labeled Bausch + Lomb ophthalmic solution; veterinary use is extra-label.
- Allergic cross-reactions with other aminoglycosides are possible.
Monitoring
Recheck persistent redness, pain or discharge; assess hypersensitivity.
Client counseling
Do not touch the bottle tip to the eye or other surfaces. Never inject into the eye.
This section supports the veterinary team's discharge discussion; it does not replace the product’s Client Information Sheet where one is required.
Storage & handling
Store at 15–25°C; keep tightly closed.
Brands, formulations & ingredient identity
Active ingredients
Neomycin sulfate · Polymyxin B sulfate · Gramicidin
Other searchable names: NeoPolyGram · Neo Poly Gram · neomycin polymyxin gramicidin
NeoPolyGram is retained as common ingredient shorthand. Verify the actual manufacturer and labeled formulation rather than interpreting the abbreviation as a guaranteed brand.
Gramicidin is the third active ingredient; it is neither bacitracin nor a steroid.
The cited product is a sterile ophthalmic solution, not a topical skin preparation.
Shared ingredients do not establish interchangeable concentrations, routes, release properties, species labeling or regional availability.
This entry is indexed by its generic ingredient name; verify the actual manufacturer and package.
References & review status
Clinical reference updated October 16, 2026. Independent veterinary or veterinary-pharmacy review not yet completed. Evidence gaps remain explicitly identified; this page does not claim equivalence to a comprehensive, professionally reviewed veterinary formulary.
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